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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IQGAP1
All Species:
17.27
Human Site:
Y1526
Identified Species:
63.33
UniProt:
P46940
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46940
NP_003861.1
1657
189252
Y1526
F
Y
G
E
Q
V
D
Y
Y
K
S
Y
I
K
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536199
1657
189148
Y1526
F
Y
G
E
Q
V
D
Y
Y
K
S
Y
I
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKF1
1657
188738
Y1526
F
Y
G
E
Q
V
D
Y
Y
K
S
Y
I
K
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509899
540
60910
N441
L
T
S
I
E
E
E
N
S
Q
R
Y
V
D
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082590
1618
184741
Y1487
F
Y
E
E
Q
V
D
Y
Y
K
S
Y
I
K
T
Zebra Danio
Brachydanio rerio
NP_001121812
1680
191619
Y1537
F
Y
Q
E
Q
I
N
Y
Y
D
T
Y
I
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203784
771
87814
V672
S
V
T
Q
L
G
E
V
S
K
K
F
L
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97
N.A.
95.9
N.A.
N.A.
28.2
N.A.
80.5
62
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
N.A.
N.A.
98.5
N.A.
98
N.A.
N.A.
30.8
N.A.
89.1
77.9
N.A.
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
6.6
N.A.
93.3
66.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
33.3
N.A.
93.3
86.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
58
0
0
15
0
0
0
15
0
% D
% Glu:
0
0
15
72
15
15
29
0
0
0
0
0
0
0
0
% E
% Phe:
72
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% F
% Gly:
0
0
43
0
0
15
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
15
0
0
0
0
0
0
72
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
72
15
0
0
72
0
% K
% Leu:
15
0
0
0
15
0
0
0
0
0
0
0
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
15
0
0
0
0
0
15
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
15
15
72
0
0
0
0
15
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% R
% Ser:
15
0
15
0
0
0
0
0
29
0
58
0
0
0
0
% S
% Thr:
0
15
15
0
0
0
0
0
0
0
15
0
0
0
72
% T
% Val:
0
15
0
0
0
58
0
15
0
0
0
0
15
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
72
0
0
0
0
0
72
72
0
0
86
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _